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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THEMIS2
All Species:
25.76
Human Site:
T53
Identified Species:
70.83
UniProt:
Q5TEJ8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TEJ8
NP_001034566.1
643
72049
T53
T
G
D
L
I
K
V
T
Q
V
R
L
Q
K
V
Chimpanzee
Pan troglodytes
XP_518734
641
73457
T52
T
G
E
V
I
K
I
T
G
L
K
V
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001112611
644
72320
T53
T
G
D
L
I
K
V
T
Q
V
R
L
Q
K
V
Dog
Lupus familis
XP_854884
688
76683
T53
T
G
D
L
I
K
V
T
Q
V
R
L
Q
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91YX0
663
74360
T53
T
G
D
L
I
K
V
T
H
V
Q
L
Q
K
V
Rat
Rattus norvegicus
XP_001064217
639
71485
E45
H
L
E
K
V
V
C
E
D
P
E
T
G
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518438
728
77913
T53
T
G
D
L
M
K
I
T
H
V
Q
L
Q
K
V
Chicken
Gallus gallus
XP_417712
576
63161
Y29
L
R
I
C
S
G
V
Y
F
Q
G
S
V
Y
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF62
675
76607
T52
T
G
D
L
L
K
V
T
E
I
T
I
S
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
93.9
68.7
N.A.
66
64.5
N.A.
46.2
42.7
N.A.
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.4
96.8
76.7
N.A.
77.9
76.3
N.A.
58
55.8
N.A.
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
100
N.A.
86.6
0
N.A.
73.3
6.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
20
N.A.
93.3
6.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
0
0
0
12
12
0
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% F
% Gly:
0
78
0
0
0
12
0
0
12
0
12
0
12
0
0
% G
% His:
12
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
56
0
23
0
0
12
0
12
0
0
12
% I
% Lys:
0
0
0
12
0
78
0
0
0
0
12
0
12
67
0
% K
% Leu:
12
12
0
67
12
0
0
0
0
12
0
56
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
12
23
0
56
12
0
% Q
% Arg:
0
12
0
0
0
0
0
0
0
0
34
0
0
12
0
% R
% Ser:
0
0
0
0
12
0
0
0
0
0
0
12
12
0
0
% S
% Thr:
78
0
0
0
0
0
0
78
0
0
12
12
0
0
12
% T
% Val:
0
0
0
12
12
12
67
0
0
56
0
12
12
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _